Plain-English translation of NCT07222969 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This clinical trial is testing a new medication called VIB305 as an injection to treat advanced solid tumors (cancers that have spread and cannot be surgically removed) in people who have failed standard treatments or are unable to receive them. The study has two phases: first, researchers will test increasing doses to find the safest and most effective dose, and then they will enroll more patients to confirm how well the medication works in specific cancer types.
Many patients with advanced solid cancers run out of treatment options or cannot tolerate standard therapies. This trial exists to see if this new medication could offer hope to those patients by safely and effectively slowing or stopping their cancer growth.
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You will receive VIB305 injections according to a treatment schedule set by the researchers. The study is divided into two stages: in the first stage, the dose will be gradually increased in small groups of patients to find the safest dose; in the second stage, larger groups will receive the recommended dose to test how well it works. Throughout the trial, you will have regular clinic visits for blood tests, imaging scans, and check-ups to monitor how you are responding and any side effects.
AI-generated summary from trial data · Aug 20, 2026 · Not medical advice
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