Plain-English translation of NCT07224451 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research is testing a new diagnostic approach using barrier-disrupting fields—a non-invasive technique that uses gentle electric pulses to help detect tumor-related proteins in blood. The study involves patients who are already scheduled for spine tumor surgery, and researchers will take blood and fluid samples before, during, and after the electric field procedure to see if they can better identify cancer-related markers.
Currently, detecting certain brain and spine tumor markers requires invasive procedures to collect fluid directly from around the spinal cord. This study aims to develop a simpler blood test that could give doctors the same diagnostic information without needing as many invasive samples, potentially making diagnosis faster and safer for patients.
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If you qualify, you would participate as part of your scheduled spine surgery. After you are asleep under anesthesia, doctors will attach special electrodes to your head and take an initial blood sample. They will then apply the barrier-disrupting field procedure, followed by additional blood samples and a sample of fluid from around your spinal cord once your surgery begins. The entire study participation happens during your already-planned surgery, with no additional visits needed.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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