Plain-English translation of NCT07224490 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Phase 1 โ Testing in a small group (usually 20โ80 people) to find a safe dose and watch for side effects.
This is a Phase 1 research study testing kisspeptin, a natural hormone in your body that sends signals to your reproductive system. Researchers want to understand how well this hormone works in people who are healthy versus those dealing with long COVID. The study involves a single injection of the medication followed by blood tests to measure how your body responds.
Long COVID and other conditions can affect the nerves and hormones that control reproduction, but doctors don't have good tools to measure this damage. This medication may help researchers understand how reproductive nerve function changes in disease, which could lead to better ways to diagnose and treat these conditions.
You likely qualify ifโฆ
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You will come in for a study visit where you'll receive a single injection of the medication under your skin. Before and after the injection, the researchers will take blood samples to measure how your body responds. The entire visit should take a few hours, and you'll go home the same day. There is no long-term commitment or multiple visits required for this Phase 1 study.
AI-generated summary from trial data ยท Jul 14, 2026 ยท Not medical advice
United States
Phase
Safety & dosing
Sponsor
Stephanie B. Seminara, MD
Collaborators
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Enrollment target
~40 participants
Started
March 2026
Primary completion
May 2030
Age range
18 Years โ 60 Years
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary โ some teams are faster than others.
Central contact
Study Coordinator
Stephanie B. Seminara, MD
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first โ no email needed to get started.