Plain-English translation of NCT07224763 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing a new type of kidney transplant using a genetically modified pig kidney called the . Researchers want to see if this treatment is safe and works well for people with end-stage kidney disease—especially those who cannot get a traditional human kidney transplant. You would receive the pig kidney transplant and be carefully monitored for 24 weeks after surgery, then followed for life.
Many people with kidney failure die while waiting for a human kidney transplant, and some are not eligible for traditional transplants due to their medical condition. This new treatment aims to offer a lifesaving option for patients who have few or no other choices.
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You would first go through a screening period (up to 52 weeks) to confirm you are eligible. Then you would receive the pig kidney transplant surgery. After surgery, you would have frequent follow-up visits over 24 weeks for safety checks and to see how well the new kidney is working. Beyond that, you would be followed for the rest of your life to monitor the transplant's health and watch for any long-term effects.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
United States