Plain-English translation of NCT07224789 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →Researchers are developing a new blood test that looks for tiny circular RNA markers in your bloodstream to detect colorectal cancer earlier and more easily than current methods. Right now, the main way to screen for colorectal cancer is colonoscopy, which is invasive and uncomfortable for many people. This study aims to create a simple blood test that could catch cancer at an earlier, more treatable stage.
Colorectal cancer is the second leading cause of cancer deaths worldwide, but many people avoid screening because colonoscopies are uncomfortable and expensive. This new blood test could offer a faster, easier, and less costly way to detect cancer early, potentially saving lives.
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If you join this study, you will donate a single blood sample (plasma) before you receive any cancer treatment. Researchers will then analyze your blood to look for circular RNA patterns that may indicate colorectal cancer. Your sample will be part of either a training group (used to identify which RNA markers are most useful) or a validation group (used to confirm the test works). The entire process involves just one blood draw and takes minimal time.
AI-generated summary from trial data · Aug 14, 2026 · Not medical advice
United States
Sponsor
City of Hope Medical Center
Enrollment target
~600 participants
Started
January 2025
Primary completion
June 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Goel Ajay, PhD
City of Hope Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.