Plain-English translation of NCT07226674 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing Juice Plus Essentials Berry Blend Capsules to see if it can help slow or prevent cognitive decline in older adults. The study is based on research showing that foods rich in certain plant compounds called flavonoids may protect brain health, and that your gut bacteria play an important role in how your body uses these compounds. Researchers want to understand whether taking this supplement can maintain or improve thinking and memory in people at risk for Alzheimer's disease.
Alzheimer's disease is becoming more common as populations age, and there are currently limited treatments available to prevent or slow it down. Earlier research suggests that the Mediterranean diet—rich in plant compounds—may help protect the brain, but scientists need to test whether a concentrated supplement of these compounds can have the same protective effect.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will take either the berry supplement or a placebo (inactive pill) daily for a set period. You will have multiple visits where researchers will check your thinking and memory, collect blood samples to study your gut bacteria and other markers, and perform an MRI brain scan. The study will also involve questionnaires about your diet and cognitive health. Your commitment will include following the study protocol carefully, not taking other probiotics or antibiotics during the study, and being willing to practice birth control if applicable.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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