Tiny implants and eye drops to lower eye pressure in severe glaucoma

This trial is testing a new surgical approach for people with severe glaucoma whose eye pressure remains too high despite using multiple eye drop medications. The procedure combines two tiny implants: the iStent Infinite, which creates a new drainage pathway inside the eye, and the iDose TR, a small implant that slowly releases the medication Travoprost directly into the eye over time. The goal is to see whether this combined approach can safely and effectively lower eye pressure while reducing or eliminating the need for daily eye drops.

Many people with severe glaucoma cannot get their eye pressure low enough using medications and laser treatments alone, and their doctors recommend more invasive surgery to prevent vision loss. This trial exists to determine whether this newer, less invasive surgical option might work as well as or better than traditional filtering surgery, while causing fewer complications.