Receive a minimally invasive freezing procedure to treat lung nodules

Receive a minimally invasive freezing procedure to treat lung nodules | stella

What is this trial?

This trial is testing cryoablation, a minimally invasive procedure that uses extreme cold to destroy lung nodules (small spots detected on imaging). The study will enroll 90 patients who have nodules that are too small or who are too frail for traditional surgery, to see whether cryoablation is safe and effective over 2 to 5 years.

Many people with early lung nodules are found through screening scans, but cannot have surgery because of age, heart or lung problems, or other health issues. This treatment offers a less invasive option, but doctors need better evidence that it works well and is safe long-term.

Do you qualify?

You likely qualify if…

you are at least 18 years old
you have been diagnosed with a small lung nodule (between 6–30 millimeters) confirmed as cancer or suspected cancer by a doctor's team
you cannot have or are unwilling to have traditional surgery
you cannot have or are unwilling to have radiation therapy
you are in generally good health (Eastern Cooperative Oncology Group performance status 0 or 1, meaning you are able to carry out normal daily activities)
you are willing to give written consent and follow the study schedule

You likely don't qualify if…

you have severe heart, lung, liver, or kidney disease that would make anesthesia unsafe
you have a bleeding disorder or very low platelet counts that cannot be corrected
you are currently enrolled in another treatment trial
you will need other cancer treatments outside this study during the trial period
your nodule is in a location where a breathing tube or needle cannot safely reach it

What participation looks like

You would receive the cryoablation procedure, which involves either passing a scope down your breathing tube or using a small needle guided by imaging to deliver freezing cold to destroy the nodule. After the procedure, you would be monitored in the hospital and then followed with imaging scans over 2 to 5 years to track whether the nodule stays gone and whether you have any complications. The study will measure how well the procedure works, whether you recover your lung function, your pain levels, and how long you stay in the hospital.

AI-generated summary from trial data · Aug 14, 2026 · Not medical advice

Testing a freezing technique for small lung nodules

What is this trial?

Do you qualify?

What participation looks like

Trial locations(2 sites)