Plain-English translation of NCT07234773 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This is one of the first times this treatment has been tested in people.
This is an early-stage trial testing a new medication called , which is given as a single injection under the skin. The study is looking at whether the medication is safe and how your body responds to it in people with rheumatoid arthritis. Researchers will follow you for up to 12 weeks (and up to 48 weeks if certain blood cell changes occur) to watch for any side effects and to see how the medication works.
Rheumatoid arthritis can be difficult to treat, and some patients don't respond well enough to existing medications. This trial is testing whether this new treatment could offer another option for people whose arthritis is still active despite current therapy.
You likely qualify if…
You likely don't qualify if…
You would receive a single injection of the medication on Day 1 of the study. After that, you would have follow-up visits over the next 12 weeks so doctors can check how you're doing and look for any side effects. Blood tests will be done to measure how your body is responding. If certain changes in your blood cells are found, you may need additional check-ins for up to 48 weeks to monitor those changes.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
Australia
Phase
Safety & dosing
Sponsor
Kali Therapeutics, Inc.
Enrollment target
~24 participants
Started
March 2026
Primary completion
February 2027
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Trial Information
Kali Therapeutics, Inc.
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