Studying Heart and Kidney Protection With a New Diabetes Medication

This is an observational study that follows patients who have both chronic kidney disease and heart failure with preserved ejection fraction (a condition where the heart doesn't pump blood out as forcefully as normal). Researchers want to see whether SGLT2 inhibitors — a class of diabetes medications — can help protect the heart and kidneys in these patients. You would either be taking this medication as part of your normal care, or you wouldn't be taking it, and the research team would carefully track your health outcomes over time.

Both kidney disease and heart failure are serious conditions that often occur together and increase the risk of heart attacks, strokes, and death. While this medication has shown promise in helping patients with these conditions, researchers need to better understand exactly how it protects the heart and kidneys in real-world patients, and to identify which patients benefit most.