Plain-English translation of NCT07242586 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This pilot study is testing whether two established trauma therapies—Prolonged Exposure (PE) and Eye Movement Desensitization and Reprocessing (EMDR)—can be safely delivered to people with schizophrenia or related conditions who are also struggling with trauma symptoms. Many people with psychotic disorders experience trauma, but these therapies are rarely offered to them because doctors worry they might make symptoms worse. This study aims to find out if these treatments can work safely for this group when delivered carefully alongside their regular psychiatric care.
People with schizophrenia often have traumatic experiences, but trauma-focused treatment is rarely given to them due to concerns about symptom destabilization and lack of training. This trial exists to test whether the new treatment is both safe and feasible in this population, and to gather information needed to design a larger, more definitive study.
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If you join this study, you will be randomly assigned to receive either Prolonged Exposure or EMDR therapy. You will attend up to 12 weekly one-on-one sessions with a trained therapist in addition to your regular OPUS care. The therapy sessions will help you work through trauma memories and situations you have been avoiding, using either repeated, gradual exposure techniques or eye-movement-based processing, depending on which group you are in. Your therapist will monitor you closely throughout to ensure your safety, and they will coordinate with your regular psychiatric team.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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