Plain-English translation of NCT07245303 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how light might help reduce pain by studying brain activity. This trial will use MRI brain scans while showing participants different types of light (white, green, and special light that targets specific eye cells) to see how the brain responds. The study includes people with chronic musculoskeletal pain and healthy volunteers to compare how their brains process pain differently.
Chronic pain affects millions of people and current treatments don't work well for everyone. This research may uncover a completely new way to manage pain through light exposure, which could lead to safer alternatives to medication.
You likely qualify if…
You likely don't qualify if…
You'll visit the research center for comprehensive testing and an MRI scan. Before the scan, researchers will test your pain sensitivity and fit a special blood pressure cuff on your calf to create a mild, controlled pain sensation. During the MRI, you'll view different colored and special light sequences for about 24 minutes while lying still in the scanner. Afterward, you'll rate your pain level. The entire visit typically takes a few hours.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States