Plain-English translation of NCT07245329 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two surgical approaches for chronic nasal polyps: standard endoscopic sinus surgery alone, or the same surgery combined with removal of lymphoid tissue in the nasopharynx (the upper throat area behind the nose). Researchers want to see if removing this additional tissue helps reduce inflammation and prevents polyps from coming back more effectively than surgery alone.
Nasal polyps can return even after surgery, causing ongoing symptoms and inflammation. This trial explores whether removing lymphoid tissue during the initial surgery might provide better long-term control and reduce the need for repeat procedures.
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If you enroll, you will have surgery performed by your doctor. Half of participants will receive standard endoscopic sinus surgery, while the other half will receive the same surgery plus removal of lymphoid tissue in the nasopharynx. After surgery, you will have follow-up visits at 1, 3, and 6 months where researchers will check your nasal inflammation, take samples to measure immune markers, and assess your symptoms and any polyp regrowth.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
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