Recruiting

Testing new breathing tests to diagnose asthma and COPD in primary care

Plain-English translation of NCT07245576 on ClinicalTrials.gov ↗ · Source last updated May 2026 · Translation generated June 2026 ·

What is this trial?

This study is evaluating whether two newer breathing tests — oscillometry and a test that measures nitric oxide in your breath — can accurately diagnose asthma or COPD in a primary care setting. Right now, doctors often need specialized equipment and expertise to diagnose these conditions, which isn't always available in regular doctor's offices. This research will compare how well these newer tests work compared to what a lung specialist would diagnose.

Many patients with breathing problems are diagnosed by their primary care doctor, but the standard breathing test (spirometry) can be difficult to perform correctly and requires special training and equipment. This study exists to see if the newer breathing tests could make it easier and faster for regular doctors to accurately diagnose asthma and COPD without needing to refer everyone to a specialist.

Do you qualify?

You likely qualify if…

you are at least 18 years old (for asthma group) or at least 40 years old (for COPD group)
you have symptoms like wheezing, cough, chest tightness, or shortness of breath, but have not been officially diagnosed with asthma or COPD
you are willing and able to provide written informed consent to participate
you can complete breathing tests during study visits

You likely don't qualify if…

you have already been diagnosed with asthma or COPD
you have used certain asthma or steroid medications in the past few months
you have other lung conditions like lung cancer, active tuberculosis, or pneumonia
you are pregnant or breast-feeding
you have had recent chest surgery or lung procedures

What participation looks like

You will visit your primary care doctor to complete two types of breathing tests: oscillometry (a gentle breathing test that measures airway resistance) and a test that measures nitric oxide in your exhaled breath. These tests are non-invasive and do not require the forceful breathing effort that traditional spirometry requires. Your results will be compared to what a lung specialist would diagnose, to see how accurate these newer tests are.

Testing new breathing tests to diagnose asthma and COPD in primary care

What is this trial?

Do you qualify?

What participation looks like

Trial locations(12 sites)