Plain-English translation of NCT07247344 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study invites hospitalized teenagers (ages 10–20) diagnosed with major depression or bipolar disorder to participate in a detailed investigation. Researchers will use brain imaging scans, behavioral monitoring, and biomarker testing to understand how depression develops and progresses over time. The goal is to discover patterns that can help doctors predict which young people will respond well to treatment and which ones are at higher risk for poor outcomes.
Despite advances in mental health treatment, doctors still struggle to predict which teenagers will respond to depression treatment and which ones face complications like chronic symptoms or suicide risk. This study aims to fill that gap by identifying brain-based and behavioral markers that can guide personalized treatment decisions for hospitalized adolescents.
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As a participant, you would complete a series of brain imaging scans (MRI), questionnaires about your mood and thinking, and behavioral assessments during your hospitalization. Researchers will track your symptoms and cognitive function over time to see how you respond to treatment. The study is observational, meaning doctors are watching and measuring—not testing a new medication or procedure—so your regular depression treatment will continue as planned.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
China
Sponsor
Jiangsu Province Nanjing Brain Hospital
Enrollment target
~1,000 participants
Started
March 2025
Primary completion
March 2029
Age range
10 Years – 20 Years
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Zexin Lin
the Affiliated Nanjing Brain Hospital, Nanjing Medical University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.