Plain-English translation of NCT07248553 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing whether the timing of levonorgestrel-containing intrauterine device (LNG-IUD) insertion during your menstrual cycle affects how often ovarian cysts develop. The medication releases a small amount of the hormone levonorgestrel directly into your uterus to reduce heavy bleeding and cramping. The study will place the device at different points in women's cycles and then monitor them for one year to see if timing makes a difference in cyst formation.
Some women develop ovarian cysts after getting this type of IUD, but doctors aren't sure if inserting it at certain times during the menstrual cycle makes this more or less likely. Understanding the best timing could help reduce unwanted side effects while keeping the benefits of the treatment.
You likely qualify if…
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If you join, you'll have an initial gynecological exam, blood tests to check your hormone levels, and an ultrasound to establish a baseline. You'll then receive the IUD insertion on a specific day of your menstrual cycle (the researchers will divide participants into four groups based on cycle timing). You'll return for follow-up ultrasounds at 3, 6, and 12 months to check whether any ovarian cysts have developed. The entire study lasts one year.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
Turkey (Türkiye)
Sponsor
Gaziosmanpasa Research and Education Hospital
Enrollment target
~60 participants
Started
June 2025
Primary completion
June 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 45 Years
Sex
Female only
Last updated on clinicaltrials.gov in November 2025.
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Central contact
ecenur çelikoğlu, md
SBÜ Gaziosmanpaşa Training and Research Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.