Plain-English translation of NCT07252687 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research is following trans men and gender-diverse individuals to learn how gender-affirming hormone therapy and mastectomy affect the psychological distress some people experience related to their breasts. The study will collect information about participants' emotional well-being and coping strategies before and as they begin these medical treatments.
Breast dysphoria — distress related to breast development — can be a serious burden for trans men and gender-diverse people, sometimes leading to depression, anxiety, and suicidal thoughts. This study exists to understand how different treatment approaches affect this specific form of distress and overall mental health.
You likely qualify if…
You likely don't qualify if…
As a participant, you would share your experiences through questionnaires and check-ins as you decide whether to pursue hormone therapy or surgery. The study specifically enrolls people before they begin these treatments so researchers can track how your physical and emotional experiences change over time. You would be helping build evidence about what coping strategies and medical approaches work best for people like you.
AI-generated summary from trial data · Aug 19, 2026 · Not medical advice
Austria
Enrollment target
~100 participants
Started
November 2025
Primary completion
November 2030
Age range
16 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Katharina Feil
Medical University Innsbruck
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.