Plain-English translation of NCT07257198 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether ticagrelor—a blood-thinning medication—works better when taken alone instead of combined with aspirin in people who have had a heart attack and are being managed with medication rather than a procedure. The trial wants to see if using just one blood thinner can reduce serious bleeding while still preventing future heart attacks and other complications.
After a heart attack, doctors typically prescribe two blood-thinning medications to prevent another event, but this combination increases the risk of dangerous bleeding. This study aims to find out if the medication alone might provide better protection by reducing bleeding risk without putting patients at higher risk for another heart attack.
You likely qualify if…
You likely don't qualify if…
You would be randomly assigned to take either ticagrelor alone twice daily plus a placebo pill once daily, or ticagrelor twice daily plus aspirin once daily. You would take your assigned medication for 12 months and attend study visits to check on your health, report any bleeding or heart problems, and have blood tests or other monitoring as needed.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
Canada