Plain-English translation of NCT07257302 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a medical device called the LIC Trainer that helps people with ALS perform breathing exercises at home. The device uses a one-way valve to gently inflate the lungs without requiring you to consciously hold your breath — something that becomes difficult as ALS progresses. The goal is to see whether using this device twice daily can help maintain your lung strength, reduce breathing problems, and possibly extend survival.
ALS weakens the muscles you use to breathe, which is one of the most serious complications of the disease. While a traditional breathing therapy exists, it doesn't work well for people with advanced ALS, especially those who have lost the ability to control their throat muscles or have had a tracheostomy. This trial exists to test whether the new device can overcome these limitations and help more people with ALS benefit from breathing therapy.
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You would use the LIC Trainer device at home, performing about 10 assisted breathing inflations twice per day. A physical therapist will teach you how to use the device and then check in with you every 3 months for the next 3 years to see how you're doing. Researchers will measure your lung function, watch for any breathing problems, and track how the device affects your quality of life and overall health.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
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