Plain-English translation of NCT07260656 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing Capsadyn®, a topical cream containing capsaicin (a natural compound from chili peppers), to see if it can reduce foot pain caused by diabetic nerve damage. Half of the participants will receive the active medication, and the other half will receive a placebo cream with no active ingredient. Neither you nor your doctor will know which cream you're using until the study ends.
Many people with diabetes experience painful nerve damage in their feet that is difficult to treat. This medication could offer a new topical option that might help reduce this pain without requiring oral medications or injections.
You likely qualify if…
You likely don't qualify if…
You will apply the study cream to your painful foot area twice per day as instructed. You'll need to wait at least 60 minutes after each application before washing your feet or filling out pain rating forms. You'll visit the clinic for assessments to track how the treatment affects your pain over time. The study is designed to enroll 80 people total, and your participation will help researchers understand whether this medication is effective and safe.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
United States