Plain-English translation of NCT07261475 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether Crocus sativus tepals water extract—a drink made from saffron flower parts—can help your body respond better to meals and manage blood sugar levels. Researchers want to know if taking this extract before eating a meal can reduce blood sugar spikes and improve other markers of metabolic health in people with obesity or prediabetes. You would try the treatment once and plain water once, with blood tests and measurements in between.
Many people with obesity and prediabetes struggle to keep their blood sugar stable after eating, which increases their risk of developing diabetes. Researchers are exploring whether this natural saffron extract might help the body handle meals better and reduce these health risks.
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You would visit the study site twice, at least one week apart. On each visit, you'll drink either the saffron extract or plain water 5 minutes before eating a small meal of white bread. Before and after the meal, researchers will take blood samples, measure your blood pressure, and assess your resting metabolism. Each visit takes a few hours, and you'll need to fast (not eat) beforehand.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
Slovenia