Plain-English translation of NCT07264790 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether , a topical medication you apply to your skin, can improve blood flow to breast tissue during reconstruction surgery. The study is for women who are having both breasts removed as a preventive measure because they carry a genetic risk for breast cancer. By comparing one breast that receives the medication to the other breast that receives a placebo, doctors hope to learn whether this treatment helps the reconstructed tissue stay healthier.
During breast reconstruction surgery, surgeons move healthy tissue to create new breasts, and sometimes that tissue doesn't get enough blood flow, which can cause complications. This study is exploring whether this medication, which is known to improve blood circulation, might help ensure the reconstructed tissue survives and heals better.
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At a pre-operative visit, you will receive two bottles labeled 'Compound A' and 'Compound B'—one contains the medication and one is a placebo, but neither you nor the research team will know which is which. You will apply one compound to each breast twice daily for 2 weeks before your scheduled surgery. Your surgery will then proceed as planned with no other changes to standard care, and doctors will assess how well the tissue is healing.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
United States