Plain-English translation of NCT07267416 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether using two brain-monitoring tools together during open-heart surgery can prevent cognitive problems—like memory loss or difficulty concentrating—that can happen after surgery. The study will use two devices: one to measure how deeply asleep you are under anesthesia, and another to measure oxygen levels in your brain. Researchers hope that by watching these two things closely during surgery and adjusting anesthesia when needed, they can reduce thinking and memory problems after you recover.
Cognitive problems after heart surgery can affect patients of any age, though they're more common in older adults. These problems can last a long time and significantly impact quality of life. Research shows that two main factors contribute to these complications: the brain not getting enough oxygen during surgery, and giving too much anesthesia. This trial tests whether monitoring both of these factors together—and making real-time adjustments—can prevent these problems from happening in the first place.
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If you join this study, you will undergo a brief thinking and memory test before your scheduled heart surgery. During your surgery, you will receive the two types of brain monitoring—one via a device on your forehead that measures oxygen, and another that measures your brain activity during anesthesia. The monitoring helps your surgical team adjust your anesthesia in real time. After surgery, you will have follow-up assessments of your thinking and memory at specific time points to see if the monitoring helped prevent cognitive problems.
AI-generated summary from trial data · Aug 26, 2026 · Not medical advice
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