Plain-English translation of NCT07271966 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether levetiracetam, a common seizure medication, causes mood changes—and whether adding a daily vitamin B6 supplement might help. Researchers want to know if vitamin B6 can reduce mood-related side effects in people with brain tumors who are already taking levetiracetam to prevent seizures. Both you and a caregiver you choose will answer questions about your mood over about 3 months to help answer this question.
Levetiracetam can sometimes cause mood problems like depression or anxiety, and patients and doctors need better ways to manage these side effects without stopping the medication that protects against seizures. This trial is exploring whether a simple, safe vitamin supplement might help reduce these mood changes.
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You will take a 100 mg vitamin B6 supplement by mouth each morning for 8 to 12 weeks, in addition to your current levetiracetam. You will fill out questionnaires about your mood at the start of the study and again at the end (8–12 weeks later). A caregiver you choose can also complete questionnaires at the same times to share their observations about any mood changes they notice. After the study ends, you can decide whether to continue taking the vitamin B6 or stop.
AI-generated summary from trial data · Aug 2, 2026 · Not medical advice
United States