Adding radiation therapy to cancer medication for advanced liver cancer

This trial is testing whether combining a targeted radiation treatment called stereotactic body radiotherapy (SBRT) with standard systemic therapy (cancer medications) works better than medication alone for people with advanced hepatocellular carcinoma (a type of liver cancer). SBRT delivers high doses of radiation very precisely to specific tumors or areas where cancer has spread. Doctors think this treatment combination might work better together because the radiation could boost how well the medication fights the cancer.

Advanced liver cancer is usually diagnosed at a stage when surgery isn't an option, and while cancer medications have helped many patients, they don't work well enough for everyone. This trial explores whether adding precise radiation therapy to the medication can improve how long patients survive and how well their cancer is controlled.