Plain-English translation of NCT07276139 on ClinicalTrials.gov ↗ ·
The PACEVALUE study is tracking thousands of patients who receive heart devices—like pacemakers, defibrillators, or specialized pacing devices—to understand who is at risk of developing a complication called pacing-induced cardiomyopathy, where the heart's pumping ability weakens over time. By collecting information from routine medical visits, device data, and patient experiences, researchers hope to create a risk prediction tool that helps doctors choose the best pacing strategy for each individual before surgery.
While these heart devices save lives, long-term pacing can sometimes weaken the heart muscle, leading to more hospitalizations and serious complications. This study exists to predict which patients are at highest risk and test whether personalized pacing approaches—including newer techniques—can prevent this problem and improve outcomes.
You likely qualify if…
You likely don't qualify if…
If you join the prospective arm, you'll be enrolled around the time of your device procedure and then followed annually for up to ten years. At each visit, doctors will collect information about your heart function, device performance, symptoms, and healthcare costs—mostly from routine care you're already receiving. If you join the retrospective arm, researchers will use your medical records and device data from care you've already had, with annual follow-up going forward.
AI-generated summary from trial data · Sep 17, 2026 · Not medical advice
Australia
Bulgaria
Croatia
Cyprus