Plain-English translation of NCT07277114 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different ways to treat severely calcified (hardened) blockages in the coronary arteries—the blood vessels that supply your heart. After doctors prepare the blockage using special techniques, participants will receive either a drug-coated balloon or a drug-eluting stent (a small mesh tube that slowly releases medication). The study wants to find out which approach works better for patients with this specific type of heart blockage.
Severely calcified coronary arteries are particularly challenging to treat because the hardened calcium can make it difficult for standard treatments to work effectively. This trial exists to determine whether the drug-coated balloon or the drug-eluting stent provides better outcomes for these difficult cases.
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You will undergo a heart catheterization procedure where doctors will prepare your calcified artery using special techniques, then randomly assign you to receive either a drug-coated balloon or a drug-eluting stent. After the procedure, you'll need to take prescribed blood-thinning medications and return for follow-up visits to check how well the treatment is working. The study will track whether you experience any complications and how your heart function improves over time.
AI-generated summary from trial data · Sep 24, 2026 · Not medical advice
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