Plain-English translation of NCT07278115 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether combining gastric bypass surgery with a procedure that cuts the vagus nerve (a major nerve controlling digestion) helps people with type 2 diabetes achieve remission better than gastric bypass surgery alone. The vagus nerve controls how your body digests food and regulates blood sugar. Researchers believe that cutting this nerve, in addition to the standard gastric bypass procedure, may improve how your body handles glucose and reduce insulin resistance.
Gastric bypass surgery alone helps many people with type 2 diabetes, but doctors want to know if they can improve those results even further. Research suggests that the vagus nerve may be contributing to insulin resistance and poor blood sugar control, so adding a procedure to interrupt this nerve's signaling might provide additional benefit beyond weight loss alone.
You likely qualify if…
You likely don't qualify if…
If you qualify and enroll, you will be randomly assigned to receive either standard gastric bypass surgery or gastric bypass surgery combined with truncal vagotomy (nerve cutting). Both procedures are performed using minimally invasive laparoscopic techniques. You will be blinded to which procedure you receive. After surgery, you will have regular follow-up appointments to monitor your diabetes remission, weight loss, and overall health, though the exact schedule is not detailed in this summary.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
Greece