Plain-English translation of NCT07278505 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
Researchers are studying how (CBD), a compound from cannabis that doesn't make you high, affects the brain's stress response system. This trial will give some young adults CBD and others a placebo (inactive pill), while using brain imaging to see how the medication affects stress-related brain activity. The goal is to understand whether this medication could become a better treatment option for people struggling with stress and anxiety.
Current anxiety medications don't work well for everyone and can cause side effects or dependency. This medication shows promise in animal and early human studies for reducing stress reactions, but we don't yet know exactly how it works in the human brain or who it might help most.
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You will visit the research clinic several times for screening, assessments, and brain imaging scans. At some visits, you'll take either the active medication or a placebo by mouth, and researchers will use MRI scans to observe how your brain responds to stress-related images or tasks. You'll also complete questionnaires about your mood, stress levels, and childhood experiences. The study will carefully monitor your safety throughout.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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