Plain-English translation of NCT07280390 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand if microplastics and nanoplastics — tiny pieces of plastic pollution we're exposed to every day — build up in livers damaged by cirrhosis. This study will examine liver tissue samples from people undergoing planned liver surgery or transplant to look for these plastic particles and understand exactly where they lodge in the liver.
Plastic pollution is everywhere in our environment and food, but doctors don't yet know if these tiny particles accumulate in diseased livers or contribute to liver damage. This research could help explain a potential connection between plastic exposure and severe liver disease.
You likely qualify if…
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If you qualify, your participation would involve donating a small piece of your liver tissue during your already-scheduled surgery or transplant procedure. The research team would then examine this tissue under a microscope and use special imaging to look for plastic particles and identify exactly where they're located in your liver. This is a one-time contribution at the time of your surgery — no additional visits or treatments are required.
AI-generated summary from trial data · Jul 2, 2026 · Not medical advice
India
Collaborators
Vellore Institute of Technology University
Enrollment target
~30 participants
Started
May 2026
Primary completion
January 2027
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Madhumita Premkumar, MD DM
PGIMER Chandigarh
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.