Plain-English translation of NCT07281846 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether branched-chain amino acid (BCAA) supplements can help patients recover better after a special surgical procedure called a transjugular intrahepatic portosystemic shunt (TIPS). The surgery is used to treat serious complications of liver disease, like dangerous bleeding and fluid buildup. Researchers want to see if taking the medication for three months after surgery improves muscle strength and overall health in patients who have both advanced liver disease and significant muscle loss.
Patients with advanced liver disease often develop serious muscle loss, which makes them more likely to have complications and worse outcomes. This treatment may help restore nutrition and muscle during recovery from liver surgery, potentially improving survival and quality of life.
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After you undergo the liver shunt surgery, you will be randomly assigned to take either branched-chain amino acid supplements or a placebo (a pill that looks identical but has no active ingredient) for three months. You will take the supplements or placebo by mouth as directed, and your doctors will monitor your recovery with follow-up visits and tests. Neither you nor your doctors will know which group you are in until the study ends, so the results will be fair and reliable.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
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