Plain-English translation of NCT07282340 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
PhITT is testing whether , a medication that reduces appetite, can help teenagers with obesity lose weight safely and effectively. Half of the participants will take the real medication daily for one year, while the other half will take a placebo (a pill with no active ingredient) so researchers can see whether the treatment actually works. All participants will also receive guidance on healthy lifestyle choices.
Obesity in teenagers has become a serious health problem, and current treatment options are limited. This trial is exploring whether this medication could be a safe and effective additional tool to help young people manage their weight alongside lifestyle changes.
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If you are selected for the trial, you will visit one of about 10 research sites across the country. You will take one pill by mouth each morning for 52 weeks (one year), then continue in the study for two more weeks to monitor how you feel after stopping the medication. At each visit, the research team will check your weight, blood pressure, heart health, and mood, and will answer any questions you have. You will also receive tips and handouts about eating better and being more active.
AI-generated summary from trial data · Aug 22, 2026 · Not medical advice
United States