Plain-English translation of NCT07285356 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether wearing compression surgical gloves during chemotherapy infusions can prevent a painful side effect called peripheral neuropathy in colon cancer patients. Oxaliplatin is a common chemotherapy drug used to treat colon cancer, but it often causes nerve damage in the hands and feet that can make everyday activities like buttoning clothes or writing very difficult. This study will see if this simple, low-cost approach using gloves can protect patients from developing this harmful side effect.
Nerve damage from chemotherapy is a serious problem that affects many colon cancer patients and can severely impact their quality of life and ability to continue treatment. Researchers have seen promising results using surgical gloves to prevent this side effect with other chemotherapy drugs, but no one has tested whether this approach works with the medication used in this trial.
You likely qualify if…
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If you join this study, you will be randomly assigned to either wear special compression surgical gloves or receive standard care without gloves. If assigned to wear gloves, you will put them on 30 minutes before each chemotherapy infusion and keep them on until 30 minutes after the infusion ends. Throughout your treatment, researchers will monitor you for signs of nerve damage and ask you to fill out questionnaires about your symptoms and how the side effects are affecting your daily life.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
Brazil
Sponsor
AC Camargo Cancer Center
Collaborators
Hospital do Cancer de Londrina
Enrollment target
~84 participants
Started
October 2025
Primary completion
September 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Virgilio Souza Silva, Medical Doctor, PhD
AC Camargo Cancer Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.