Plain-English translation of NCT07286643 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether using portable ultrasound imaging of your heart can help doctors decide how much fluid to give you if you develop a severe infection while managing cirrhosis (liver scarring). The new approach, called point-of-care echocardiography, lets doctors see how your heart is working in real time, rather than relying only on blood pressure numbers. The goal is to see if this ultrasound-guided method helps patients recover better and survive longer.
Patients with cirrhosis who get severe infections are at very high risk because their bodies handle fluids differently than people with healthy livers. Doctors currently use standard blood pressure targets to guide treatment, but this approach doesn't always work well for cirrhosis patients. This trial is testing whether seeing the heart's actual function with ultrasound can lead to better, safer fluid treatment decisions.
You likely qualify if…
You likely don't qualify if…
You will be admitted to the ICU and randomly assigned to receive either ultrasound-guided fluid management or standard care. If you are in the ultrasound group, doctors will use portable heart ultrasound to monitor how your heart is responding to fluids and adjust treatment accordingly. Both groups will receive antibiotics and other standard intensive care; the main difference is how doctors decide when and how much fluid to give you. Your care will continue as long as you need ICU-level treatment for your infection.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
India