Plain-English translation of NCT07287748 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new medication called , a radioactive treatment designed to target and destroy thyroid cancer cells that have spread to other parts of the body. The study is divided into two phases: first, doctors will carefully test different doses to find the safest effective amount, and then they will compare two dose levels in a larger group of patients to see which works best.
Standard treatments for advanced thyroid cancer don't work for all patients, and some people can't tolerate them because of side effects. This medication represents a new approach using targeted radiation to attack cancer cells, offering hope for patients whose cancer has become resistant to existing therapies.
You likely qualify if…
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In the first phase, you would receive a single dose of the medication and be closely monitored to see how your body responds and to identify the best dose to use. In the second phase, a larger group of patients would be randomly assigned to receive either the highest safe dose or a slightly lower dose, with multiple treatments given over time. Throughout the trial, you would have regular check-ups, blood tests, and imaging scans to track how the treatment is working and monitor for side effects.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
Japan