Two nerve block approaches for knee replacement pain relief

This trial is testing two different approaches to pain control during and after knee replacement surgery, both using nerve blocks—numbing injections that target specific nerves around the knee. Both approaches combine the same foundational nerve block (adductor canal block) with one of two additional techniques: either a sacral erector spinae plane block or an iPACK block. The goal is to figure out which combination works better at keeping patients comfortable after surgery while preserving their ability to move and strengthen their leg.

Knee replacement surgery can cause significant pain after the operation, which can slow down recovery, delay rehabilitation, and sometimes lead to increased use of opioid pain medications. Doctors want to find the most effective nerve-blocking strategy that provides excellent pain relief while minimizing side effects and keeping patients' leg strength intact.