Plain-English translation of NCT07289399 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Psoriasis research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether adding regular treadmill walking to a low-calorie diet and metformin medication can help women who have both psoriasis (a chronic skin condition) and polycystic ovary syndrome, or PCOS (a hormone disorder affecting the ovaries). The study will compare two groups: one that walks on a treadmill three times a week plus follows the diet and takes the medication, and another that follows only the diet and medication without the walking component.
Both psoriasis and PCOS are related to inflammation and weight, and researchers want to know if adding exercise to standard treatment can improve outcomes better than diet and medication alone.
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If you join, you will be in the study for 12 weeks. You will follow a low-calorie diet and take metformin medication. Depending on which group you're assigned to, you may also walk on a treadmill for 40 minutes, three times per week. The researchers will check on your skin condition, hormone levels, and overall health throughout the study to see how the combination of treatments works.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Egypt
Sponsor
Cairo University
Enrollment target
~40 participants
Started
October 2025
Primary completion
May 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
35 Years – 45 Years
Sex
Female only
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Ali MA Ismail, lecturer
Cairo University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.