Testing a new gene therapy injection for ALS

This trial is testing INS1202, a new gene therapy treatment delivered as a single injection into the spinal fluid of people with ALS. Researchers want to understand if this treatment is safe and how it works in the body. The study will enroll about 23 participants and test three different dose levels to find the right amount.

ALS is a serious disease that gradually weakens muscles and affects movement. Current treatments help slow the disease but don't stop it. This medication aims to address the genetic causes of ALS, particularly in people with SOD1 mutations, and offers hope for a new treatment approach.