Monthly blood tests to track disease activity in treated MS

This trial is testing whether a protein marker called neurofilament-light chain (NfL), measured from your blood each month, can help doctors detect MS disease activity that MRI scans might miss. Right now, doctors usually check disease activity with yearly brain MRI scans, but these scans are expensive, time-consuming, and require contrast dye that builds up in your brain over time. The study wants to see if simple monthly blood tests could catch treatment failures earlier and help your doctor switch to stronger medications before you have a relapse.

Current monitoring methods for MS rely on yearly MRI scans, which have limitations: they're costly, they don't detect all hidden disease activity, and the contrast dye used can accumulate in your brain. This study exists to see if monthly blood tests could give doctors a faster, safer way to catch when your treatment isn't working well, so they can adjust your therapy before you get sicker.