Try a fiber supplement combined with a calorie-restricted diet for four weeks

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Recruiting

What is this trial?

This trial is testing whether beta-glucan, a natural dietary fiber, helps women lose weight and fat more effectively when combined with a low-calorie, lower-carbohydrate diet. Researchers want to see if this fiber supplement also helps control hunger and affects the hormones that regulate appetite. Half of the participants will receive the actual fiber supplement while the other half will receive a placebo (an inactive substance), and neither the participants nor the researchers will know who gets which until the study ends.

Many people struggle with weight loss and controlling hunger when dieting, and some stop dieting because they feel too hungry. This research explores whether this medication might help make weight loss easier and more sustainable by reducing hunger signals in the body.

Do you qualify?

You likely qualify if…

you are a woman aged 18 to 60 years old
you are overweight or have obesity, with a BMI between 25 and 39.9
your body weight has been stable for at least three months before joining
you exercise fewer than 75 minutes per week (you are relatively sedentary)

You likely don't qualify if…

you are a current smoker
you have an irregular menstrual cycle
you are pregnant or breastfeeding
you follow a vegan, vegetarian, or restricted diet outside of typical Western eating patterns
you are currently taking dietary supplements

What participation looks like

You would first attend a screening visit where researchers measure your height, weight, and resting metabolic rate, and ask about your health history. Then you would begin a 4-week intervention period where you follow a low-calorie, lower-carbohydrate diet and take either the fiber supplement or a placebo daily. During this time, you will have visits where researchers measure your weight, body composition, and hunger levels, and collect blood samples to check appetite-related hormones. The entire study lasts about 4 weeks plus the initial screening.

Beta-glucan fiber supplement with a reduced-calorie diet for weight loss in women

What is this trial?

Do you qualify?

What participation looks like

Trial locations(1 site)