Recruiting

AI-Guided Relaxation Training for Pain Relief in Postmenopausal Women

Plain-English translation of NCT07302750 on ClinicalTrials.gov ↗ ·

What is this trial?

This trial is testing whether relaxation and breathing training can help reduce pain in postmenopausal women who experience ongoing muscle and joint pain. You'll be randomly assigned to one of three groups: one group will learn relaxation and breathing techniques from a physiotherapist in person, another group will use an AI-powered app to guide them through similar exercises, and a third group (control) will receive general information only. The study lasts eight weeks and aims to see if structured training—especially the AI-assisted version—can ease pain and improve your overall quality of life.

After menopause, drop in hormone levels can lead to muscle weakness, bone loss, and increased pain in muscles and joints. Research shows that relaxation and breathing exercises can reduce pain and stress, but it's unclear whether an AI app can be just as helpful as working with a trained therapist.

Do you qualify?

You likely qualify if…

you are between 45 and 65 years old
you have not had a menstrual period for at least 12 months (natural menopause)
you have experienced ongoing muscle or joint pain for at least 3 months and rate it at least 4 out of 10 in severity
you are using only standard over-the-counter or prescribed pain medications—not opioids or other specialized pain drugs
you own a smartphone or tablet and can listen to audio recordings and join online sessions

You likely don't qualify if…

you had menopause caused by surgery or medication rather than naturally
you regularly take opioid painkillers, anti-seizure medications, or antidepressants for pain
you have serious heart disease, cancer, metabolic disorder, or neurological conditions that are not well controlled
you had major surgery or severe injury within the past 3 months
you have a BMI of 40 or higher

What participation looks like

If you're selected, you'll be randomly placed into one of three groups for eight weeks. The physiotherapist group will meet face-to-face with a trained therapist who teaches relaxation and breathing techniques. The AI group will use a smartphone or tablet app that delivers similar guided exercises. The control group will receive general information but no structured training. Throughout the study, you'll be asked about your pain levels and quality of life to see if the training makes a difference.

AI-Guided Relaxation Training for Pain Relief in Postmenopausal Women

What is this trial?

Do you qualify?

What participation looks like

Trial locations(1 site)