Plain-English translation of NCT07304466 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
During liver transplant surgery, dangerous pressure can build up in the blood vessels of the liver, leading to excessive bleeding and other serious complications. This trial compares two medications— and —to see which one works better at reducing this pressure and improving outcomes for patients receiving a living donor liver transplant. Both medications have been used for this purpose, but researchers want to know which is more effective.
High pressure in liver blood vessels during transplant surgery can cause severe bleeding, kidney injury, and the need for blood transfusions. This study aims to find out which of these two medications better reduces that pressure and prevents these dangerous complications.
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If you join this study, you will be randomly assigned to receive one of the two medications during your scheduled liver transplant surgery. The medication will be given intravenously (into your vein) starting before the surgery begins. Your surgical team will measure the pressure in your liver blood vessels at several points during the operation to see how well the medication is working. Your participation is part of your standard surgical care, and the study compares how these two common treatments perform.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
Turkey (Türkiye)