Plain-English translation of NCT07304505 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether Align Extra Strength Probiotic Supplement, a commercial probiotic containing Bifidobacterium longum, can help improve outcomes in people with rheumatoid arthritis. Researchers want to understand how this medication affects the gut bacteria and overall disease symptoms. You would take the medication daily for 6 weeks while providing samples and visiting the clinic for checkups.
Rheumatoid arthritis is a chronic condition that causes joint pain and inflammation, and current treatments don't work equally well for everyone. Recent research suggests that gut bacteria may play a role in how the immune system responds, so this trial is exploring whether this medication might offer additional benefit for people already receiving standard RA treatment.
You likely qualify if…
You likely don't qualify if…
You would take the probiotic supplement by mouth every day for 6 weeks. During the first 3 weeks, you would collect stool samples every other day at home; during weeks 4–6, you would collect samples twice weekly. You would visit the clinic at the start, at week 3, and at week 6 for checkups and blood or other tests to see how the medication is affecting you.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
Ancilia Biosciences
Enrollment target
~50 participants
Started
November 2025
Primary completion
March 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Stacey Boetto, DNP, FNP-C
Ancilia Biosciences
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.