Plain-English translation of NCT07309718 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying a new way to use MRI scans to predict stroke risk in people who have narrowed arteries inside the brain. This condition, called intracranial atherosclerotic stenosis, can lead to stroke, but doctors don't always know which patients are at highest risk. This trial will test whether a specialized MRI measurement—called the MRI-derived pressure ratio—can help doctors identify who needs more aggressive treatment.
Many patients with narrowed brain arteries don't have another stroke, but some do—and doctors currently have limited tools to tell the difference. This trial exists to see whether the new MRI measurement can safely and accurately predict which patients are most at risk, so doctors can tailor treatment more precisely.
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If you join, you will visit the study center for an initial evaluation and then return for follow-up visits at 1 month, 6 months, and 12 months after enrollment. During these visits, you will receive standard stroke prevention medications (blood thinners and cholesterol medications) and undergo specialized imaging tests, including MRI scans and possibly ultrasound or CT scans, to measure blood flow and artery narrowing. The study will track whether you have a stroke or other health events over the year of follow-up.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
China
Sponsor
Xuanwu Hospital, Beijing
Collaborators
Xuanwu Hebei Hospital, Xuanwu Xiongan Hospital
Enrollment target
~400 participants
Started
December 2025
Primary completion
December 2027
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in December 2025.
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Central contact
Jichang Luo, M.D.
Xuanwu Hospital, Beijing
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.