Plain-English translation of NCT07309952 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new combination approach for advanced lung cancer that has spread to lymph nodes on the opposite side of the chest. You would receive , an immunotherapy medication that helps your body fight cancer, along with chemotherapy and targeted radiation therapy, all before surgery. The goal is to shrink the cancer enough so that surgery can remove it completely and give you a chance to be cured.
Some patients with advanced lung cancer have cancer that spreads to lymph nodes on the opposite side of the chest, which makes surgery very difficult or impossible. This trial is testing whether this new combination of treatments can shrink these hard-to-reach lymph nodes before surgery, making curative surgery possible for more patients.
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You would first receive targeted radiation therapy to your lung tumor, followed by two cycles of the medication combined with chemotherapy before undergoing surgery. During treatment, you will have regular clinic visits for monitoring, blood tests, and imaging scans to see how well the treatment is working. After surgery, you will continue follow-up visits for up to 5 years to monitor your recovery and watch for any signs of cancer returning.
AI-generated summary from trial data · Aug 8, 2026 · Not medical advice
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