Plain-English translation of NCT07314229 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is looking at how a newer cystic fibrosis medication called Elexacaftor-Tezacaftor-Ivacaftor affects the ability to exercise and breathe during physical activity. The medication has already been shown to improve lung function and quality of life in people with CF. This study wants to understand whether the medication also helps people exercise better and breathing more comfortably during activities like walking.
While this medication has greatly improved lung health and reduced serious CF flare-ups, doctors don't yet fully understand how it affects exercise capacity and whether people can breathe more easily when they're physically active. This study will help fill that gap in understanding.
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If you join this study, you will complete a 6-minute walking test—a simple exercise test where you walk as far as you can in 6 minutes while doctors monitor your breathing and how your lungs perform. The study will track how many people on this medication experience breathing limitations during exercise and look for patterns in who is affected. You'll visit one of two specialized cystic fibrosis treatment centers to complete the test.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
France