Plain-English translation of NCT07318727 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing three different approaches to help overweight patients with endometrial cancer manage their weight during fertility-preserving treatment. The three approaches are: intermittent fasting (eating normally 5 days a week, fasting 2 non-consecutive days), a low-calorie balanced diet (around 1000–1200 calories per day), or standard self-directed weight management. The study wants to see which approach works best for helping patients lose weight, improve their metabolism, and support better cancer outcomes.
Being overweight makes endometrial cancer harder to treat and reduces the chances of pregnancy after fertility-sparing treatment. This trial exists to find out which eating plan — if any — helps overweight patients lose weight most effectively while protecting their ability to have children in the future.
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If you join this study, you will be randomly assigned to one of three groups: the intermittent fasting group, the low-calorie balanced diet group, or the standard care group. The study will track your body weight and composition, measure metabolic markers (like blood sugar and cholesterol), and monitor your cancer outcomes over time. You will need to follow your assigned eating plan and attend visits for measurements and blood tests.
AI-generated summary from trial data · Jul 12, 2026 · Not medical advice
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