New ultrasound method to measure liver fat in fatty liver disease

Plain-English translation of NCT07321925 on ClinicalTrials.gov ↗ · Source last updated January 2026 · Translation generated June 2026 · How we translate trials

What is this trial?

This pilot study is testing a new ultrasound device called the FLIP CID system that measures how much fat has built up in your liver. Researchers will compare the results from this new device to MRI scans — which are considered the gold standard for measuring liver fat — to see if the ultrasound method is accurate and reliable.

Many people have fatty liver disease, but current ways of measuring liver fat can be expensive, time-consuming, or require specialized equipment. This trial is exploring whether a simpler ultrasound-based approach could provide a faster and more accessible way to detect and monitor liver fat in patients.

Do you qualify?

You likely qualify if…

you are 18 years old or older
you are able to understand and read English and sign a consent form
you can lie still (flat or on your side) for about 20 minutes and hold your breath briefly
you can tolerate both ultrasound and MRI scans without difficulty

You likely don't qualify if…

you have metal or electronic implants such as a pacemaker, metal clips, hip implants, or neural stimulation devices
you are pregnant or might become pregnant during the study
you have liver diseases other than fatty liver disease, such as cirrhosis, liver cancer, or fluid buildup in your abdomen
you have a BMI greater than 50 kg/m² or significant anatomical factors that would prevent clear ultrasound imaging of your liver
you have broken or injured skin in the upper right area of your abdomen where the measurement would take place

What participation looks like

If you qualify, you would receive both an ultrasound scan using the new FLIP CID device and an MRI scan on the same day or during the study period. The ultrasound typically takes less time and involves lying still while the device measures your liver fat. The MRI is a standard imaging test that provides a detailed picture for comparison. Both scans are non-invasive — nothing is injected or inserted — and you should expect to spend a few hours total at the study site.

AI-generated summary from trial data · Jun 6, 2026 · Not medical advice

Trial locations(1 site)

United States

ENDRA Life Sciences, Ann Arbor, Michigan