Testing a new medication to slow muscle weakness in early ALS

This trial is testing a medication called pridopidine to see if it can help slow the progression of ALS (amyotrophic lateral sclerosis). The study will compare pridopidine against placebo (a dummy pill with no medicine) in about 500 people with early, rapidly progressing ALS. Researchers want to understand whether this medication can help preserve muscle strength and function better than placebo.

ALS is a disease that causes muscle weakness and loss of function, and there are very few treatment options available. This medication is being tested because early research suggests it might help slow disease progression in people with early-stage ALS.