Plain-English translation of NCT07324057 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether giving children with autism a calming medication called dexmedetomidine or esketamine through a nasal spray 30 minutes before surgery can reduce difficult behaviors after they wake up. Some children with autism experience more anxiety and behavioral challenges after surgery, and this study wants to see if these medications can help prevent that.
Children with autism often feel extra anxious before surgery and may have more trouble with their behavior afterward—things like sleep problems, irritability, or fear. Doctors want to know if giving this medication before surgery can reduce these struggles and help children recover more smoothly.
You likely qualify if…
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If you enroll, your child will receive a single nasal spray dose about 30 minutes before their scheduled surgery—either the test medication or a salt-water spray (placebo). The surgery itself happens as planned with standard anesthesia. After surgery, doctors will check on your child's behavior over the next week to see if the spray made a difference in how they recover.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
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